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Am J Trop Med Hyg ; 103(4): 1593-1596, 2020 10.
Article in English | MEDLINE | ID: covidwho-890582

ABSTRACT

Coinfection of SARS-CoV-2/Mycobacterium tuberculosis (MTB) in patients with HIV/AIDS has not been previously reported. Here, we present two cases of coinfection of SARS-CoV-2 and MTB in patients with HIV. The first case is a 39-year-old patient who was admitted with a 7-day history of fever, myalgia, headache, and cough. The second patient is a 43-year-old man who had a 1-month history of cough with hemoptoic sputum, evolving to mild respiratory distress in the last 7 days. Both patients already had pulmonary tuberculosis and subsequently developed SARS-CoV-2 infection during the 2020 pandemic. Nonadherence to antiretroviral treatment may have been a factor in the clinical worsening of the patients.


Subject(s)
Coronavirus Infections/microbiology , Cough/microbiology , HIV Infections/microbiology , Patient Compliance/psychology , Pneumonia, Viral/microbiology , Respiratory Distress Syndrome/microbiology , Tuberculosis, Pulmonary/microbiology , Adult , Anti-HIV Agents/therapeutic use , Betacoronavirus/pathogenicity , COVID-19 , Coinfection , Coronavirus Infections/drug therapy , Coronavirus Infections/immunology , Coronavirus Infections/virology , Cough/drug therapy , Cough/immunology , Cough/virology , HIV/pathogenicity , HIV Infections/drug therapy , HIV Infections/immunology , HIV Infections/virology , Humans , Male , Mycobacterium tuberculosis/pathogenicity , Pandemics , Pneumonia, Viral/drug therapy , Pneumonia, Viral/immunology , Pneumonia, Viral/virology , Respiratory Distress Syndrome/drug therapy , Respiratory Distress Syndrome/immunology , Respiratory Distress Syndrome/virology , SARS-CoV-2 , Tomography, X-Ray Computed , Tuberculosis, Pulmonary/drug therapy , Tuberculosis, Pulmonary/immunology , Tuberculosis, Pulmonary/virology
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